Precise • Cost-efficient • Time-saving
Our new, liquid-stable and ready-to-use reagent Procalcitonin FS is now available.
DiaSys Procalcitonin FS is a particle enhanced immunoturbidimetric assay for the determination of Procalcitonin (PCT) in serum and plasma on photometric systems. The assay offers a measuring range from 0.2 ng/mL to 50 ng/mL and high precision at clinical cut-off levels for sepsis. No prozone effect was observed up to 1000 ng/mL. Furthermore, Procalcitonin FS has an outstanding onboard und calibration stability. The assay performance is complemented by high tolerance to endogenous interferents and common therapeutics used in sepsis management.
Procalcitonin is a 116 amino acid prohormone of calcitonin. In healthy individuals, serum levels of PCT are very low (< 0.05 ng/mL); upon stimulation by bacterial toxins and inflammatory cytokines, PCT is expressed in nearly all tissues. In patients with systemic bacterial infections, such as sepsis, serum PCT levels rise from
< 0.1 ng/mL up to 1000 ng/mL within a few hours.