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Molecular biomarkers
Polymerase chain reaction (PCR)
Other molecular diagnostics testing
Product category: Molecular biomarkers, Polymerase chain reaction (PCR)
Product Highlights
Stable and Reliable:Closed tube detection, avoid contamination.
High Sensitivity: The detection can reach as low as 1% in 10 ng DNA.
Easy Operation: One step operation, only 90 minutes to finish the detection.
Good Reproducibility: Can be performed in the general PCR Labs. Results with good reproducibility canbe easily obtained without special training.
Product category: Molecular biomarkers, Other molecular diagnostics testing
Advantages and Characteristics
Easy Operation: With independent patented RingCap® technology, library construction can be done in only two steps.
Rapid Detection: Library construction takes only 3.5 hours, only 2 working days from sample processing to reporting.
High Sensitivity:10000x sequencing depth. Up to 0.1% of sensitivity. Achieving the drug resistance monitoring for the liquid biopsy samples.
Comprehensive Detection: Detecting 13 mutated genes, covering 482 existing targeted drug-related COSMIC loci in one time. Comprehensive analysis the genetic information of non-small cell lung cancer andcolorectal cancer. To guide the use of targeted drugs which is recommended by the domestic and foreign authoritative institutions.
Detection significance
• Assist clinicians to select targeted drugs for patients.
• Predict efficacy and resistance of targeted drugs.
Product category: Molecular biomarkers, Other molecular diagnostics testing
Technical Highlights
Easy Operation: With independent patented RingCap® technology, library construction can be done in only two steps.
Rapid Detection: Library construction takes only 3.5 hours, only 2 working days from sample processing to reporting.
Accurate and Reliable: The targeting fragments are amplified by specific primers. Applicable to both paraffin embedded tissues and peripheral blood samples.
Comprehensive Inspection: As high-frequency mutant hotspots does not exist in the BRCA1/2genes, this kit achieves the whole exomes sequencing, ensuring the integration of the detection.
Detection Significance
1. Prediction
*The detection results can be used for the risk assessment of familial inherited breast cancer,and helping clinicians to select suitable prophylactic surgery or drugs.
2. Drug Guidance
*The breast/ovarian patients with BRCA 1/2 mutations will be more sensitive to orapani and other PARP inhibitors.
*The breast/ovarian patients with BRCA 1/2 mutations will be more sensitive to platinum-based treatments.
Product category: Molecular biomarkers, Polymerase chain reaction (PCR)
Product category: Molecular biomarkers, Polymerase chain reaction (PCR)
Detection Significance
● For the patients taking EGFR-TKI,the detection results of K-ras status can be used to predict the drug efficacy.
● For the patients with metastatic colorectal cancer, the detection of K-ras status is recommended before starting cetuximab treatment.
Technical Highlights
Easy operation: One-step operation. 90 minutes of the whole process.
High Sensitivity: Accurate detection of single copies of mutated DNA samples as little as10ng genome.
Good Reproducibility: Can be performed in the general PCR Labs. Results with good reproducibility can be easily obtained without special training.
Advanced Technology: R&D based on independent patented PAP-ARMS technology.