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Seramun Diagnostica GmbH

Spreenhagener Str. 1, 15754 Heidesee
Germany
Telephone +49 33767 79110
Fax +49 33767 79199
info@seramun.com

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Contact

Peter Lobeda

Managing Director

Phone
+49 33767 79165

Email
peter.lobeda@seramun.com

Klemens Löster

R&D Project Manager SeraSpot

Phone
+49 33767 79136

Email
klemens.loester@seramun.com

Michaela Schulze

International Sales

Phone
+49 33767 79130

Email
michaela.schulze@seramun.com

Visit us

Unsettled / NN

16.11.2020

Topic

all-day

Meet the Experts every day from 16-19 November 2020

GOING DIGITAL AT MEDICA 2020 - MEET US THERE!
Meet our experts virtually - from 16 to 19 November 2020

You can get in touch with one of our experts via Zoom or Team from 16 to 19 November 2020. Simply schedule a meeting with us - via e-mail: messe@seramun.com - our experts are looking forward to hearing from you!

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17.11.2020

Topic

all-day

Meet the Experts every day from 16-19 November 2020

GOING DIGITAL AT MEDICA 2020 - MEET US THERE!
Meet our experts virtually - from 16 to 19 November 2020

You can get in touch with one of our experts via Zoom or Team from 16 to 19 November 2020. Simply schedule a meeting with us - via e-mail: messe@seramun.com - our experts are looking forward to hearing from you!

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18.11.2020

Topic

all-day

Meet the Experts every day from 16-19 November 2020

GOING DIGITAL AT MEDICA 2020 - MEET US THERE!
Meet our experts virtually - from 16 to 19 November 2020

You can get in touch with one of our experts via Zoom or Team from 16 to 19 November 2020. Simply schedule a meeting with us - via e-mail: messe@seramun.com - our experts are looking forward to hearing from you!

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19.11.2020

Topic

all-day

Meet the Experts every day from 16-19 November 2020

GOING DIGITAL AT MEDICA 2020 - MEET US THERE!
Meet our experts virtually - from 16 to 19 November 2020

You can get in touch with one of our experts via Zoom or Team from 16 to 19 November 2020. Simply schedule a meeting with us - via e-mail: messe@seramun.com - our experts are looking forward to hearing from you!

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13:40 - 13:50

MLF: Novel Macroarray and RBD-specific ELISA for the detection of SARS-CoV-2-specific antibodies

Session Innovative COVID-19 diagnostics               

Novel Macroarray and RBD-specific ELISA for the detection of SARS-CoV-2-specific antibodies
by Dr. rer. nat. Mathias Schlegel

https://events.medica.de/de/veranstaltung/mlf-novel-macroarray-and-rbd-specific-elisa-for-the-detection-of-sars-cov-2-specific-antibodies

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Our range of products

Product categories

  • 03  Diagnostic tests
  • 03.02  Immunochemistry testing, immunology testing
  • 03.02.01  Immuno assay testing
  • 03  Diagnostic tests
  • 03.05  Infectious immunology testing
  • 03.05.02  Microbiological diagnosis, virology, equipment and systems for

Microbiological diagnosis, virology, equipment and systems for

  • 03  Diagnostic tests
  • 03.07  Other diagnostics

Our products

Product category: Microbiological diagnosis, virology, equipment and systems for

Serazym® Anti-SARS-CoV-2 RBD IgG

The entry of SARS-CoV-2 into its target cells depends on binding between the receptor-binding domain (RBD) of the viral spike protein and its cellular receptor, angiotensin-converting enzyme 2. Many investigations show a clear correlation between the presence of neutralizing antibodies and the detection of RBD-specific antibodies. To improve the SARS-CoV-2 antibody diagnostic and the detection of potentially neutralizing or protective antibodies, the Seramun Diagnostica GmbH has successfully developed an ELISA which is able to detect SARS-CoV-2-RBD-specific IgG antibodies. This Anti-SARS-CoV-2-RBD ELISA has so far been tested with 64 sera of COVID-19 patients and 218 negative blood donor sera (incl. Control groups → CMV, EBV, HBV, HCV, RF, pregnant woman). A Sensitivity of 90.6% and specificity of 100% were determined. RBD is a highly specific antigen for the SARS-CoV-2-antibody diagnostic. Antibody-crossreactivities with other human- and animal-pathogenic coronaviruses are unlikely. Semi-quantification of RBD-specific antibodies is possible with the assay and of increasing importance in the context of vaccination control. Furthermore, the assay is applicable for animal sera e.g. monkey, mouse, and hamster for vaccine-, drug-research and veterinary research.

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Product category: Microbiological diagnosis, virology, equipment and systems for

SeraSpot®Anti-SARS-CoV-2 IgG / IgA

The Seramun Diagnostica GmbH developed two macroarrays for the SARS-CoV-2 antibody diagnostic. The SeraSpot® Anti-SARS-CoV-2 IgG and IgA assay contains a total of 4 different SARS-CoV-2-specific antigens (nucleocapsid protein, spike protein, spike S1 domain, receptor binding domain). With this product the independent detection of NP-, Spike-, Spike-S1- and RBD- IgG or IgA antibodies from one sample in one well is possible. The detection of different antibodies could be interesting to determine potential risk infections, to discriminate active from past infections, for antibody profiling or to detect possible protective antibodies. The SeraSpot microarray could greatly increase the specificity of the SARS-CoV-2 serological diagnostic. Both assays could be applicable as SARS-CoV-2 confirmation test for the serology diagnostic.

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Product category: Immuno assay testing

Seramun Substrates and Stabilizers

The ready-to-use TMB substrates of the SeramunBlau® line include products for colorimetric ELISA applications as well as for membrane immunoassays and microarrays. The precipitating substrates form color complexes which clearly stand out against the pale background color. All substrates are based on the enzymatic reaction of horseradish peroxidase. SeramunGelb® products can be used for colorimetric ELISA application while SeramunPurple® prec, being used in the membrane area, offers a high color contrast and stable dark red precipitates through AP-based turnover reactions.

Seramun stabilizers are being used for stabilization of HRP and AP conjugates as well as for stabilization of biomolecules and sensitive protein mixtures. Protein-free stabilizers such as SeramunBlock NP 5x conc. strongly reduce the background effects of biological components and are therefore an important part of the Seramun Diagnostica product range.

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Product category: Other diagnostics

Seramun Antibodies and Antigens

The Seramun antibody service offers production, purification and labeling of poly- and monoclonal antibodies. For this purpose, Seramun has a modern animal husbandry. Required immunization antigens are produced directly on site in the antigen service area. For this purpose, Seramun is working with different expression systems. Different methods for purifying the antigens and antibodies are available. The reactivity of the generated antibodies is checked via ELISA. A comprehensive quality control of the antigens is carried out at the Seramun premises.

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About us

Company details

As a biopharma­ceutical company, we have been producing various labora­tory diagnos­tics and research reagents for more than 25 years. We specialize in providing to our customers premium­ quality products for human medical and veterinary diagnostics, which are developed and produced in our Germany-based labora­tory and meet the requirements of labora­tories of various sizes through individual customi­zation.

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Company data

Sales volume

1-9 Mio US $

Export content

max. 25%

Number of employees

50-99

Foundation

1992

Area of business

Diagnostics